Research progress on the mechanism of microRNA in papillary thyroid carcinoma
- VernacularTitle:microRNA在甲状腺乳头状癌中作用机制的研究进展
- Author:
Qingqing QIN
;
Tingting LI
;
Yongqin ZHENG
;
Jundong HE
- Keywords:
miRNA;
papillary thyroid carcinoma;
signaling pathway
- From:
Basic & Clinical Medicine
2017;37(8):1184-1189
- CountryChina
- Language:Chinese
-
Abstract:
microRNAs (miRNAs) are a class of small non-coding,single-stranded RNAs,which regulate gene expression by binding messenger RNA (mRNA).Thyroid cancer is the most common endocrine cancer.Papillary thyroid carcinoma (PTC) is a common type of thyroid cancer,and its incidence has dramatically increased worldwide.Recent evidence suggests that miRNAs play an important role in thyroid carcinogenesis,development and prognosis,especially in PTC.