Shear-wave elastic modulus for differential diagnosis of benign and malignant breast lesions:Meta-analysis
10.13929/j.1003-3289.201606167
- VernacularTitle:剪切波弹性模量鉴别乳腺良恶性肿块的Meta分析
- Author:
Xinhua DING
;
Ping XU
;
Haiyan LEI
;
Jiabing WANG
;
Minghui TONG
;
Haiyong WANG
;
Lei TONG
- Keywords:
Elasticity imaging techniques;
Breast neoplasms;
Meta-analysis
- From:
Chinese Journal of Medical Imaging Technology
2017;33(3):404-409
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the value of shear-wave elastic modulus for differential diagnosis of benign and malignant breast lesions using Meta-analysis.Methods Relevant Chinese and foreign articles about shear-wave elastography for differentiating benign and malignant breast lesions were collected from the literatures published before Apr.2016.Meta-analysis was conducted to assess the overall ability of the shear wave elastic modulus including Emax,Emea,Eratio and Esd.Results Totally 31 studies were brought into the Meta-analysis.The summarized sensitivity (SSEN) and summarized specificity (SSPE) of Emax were 0.87(95％CI [0.83,0.91]) and 0.91 (95％CI [0.87,0.93]).The SSEN and SSPE of Emea were 0.84 (95％CI [0.77,0.89]) and 0.88 (95％CI [0.84,0.91]),The SSEN and SSPE of Eratio were 0.88(95％CI [0.83,0.91]) and 0.87 (95％CI [0.80,0.91],the SSEN and SSPE of gsd were 0.85 (95％CI [0.80,0.89]) and 0.90 (95％CI [0.85,0.94]).The summarized receiver operator characteristic analysis showed that the area under the curve of E E Eratio and Esd were 0.95,0.93,0.93 and 0.93.Conclusion The shear wave elastic modulus contribute to differentiate benign and malignant breast lesions.Among these indices,Emax is the best one.
