Ultrasonographic and pathological features of metaplastic carcinoma with squamous cell component of breast
10.13929/j.1003-3289.201608140
- VernacularTitle:含有鳞状细胞癌成分的乳腺化生性癌的超声与病理特征
- Author:
Lei YAN
;
Xiang XU
;
Xiaojian YE
;
Xingfu WANG
;
Xiaoyu CHEN
;
Rongquan XU
- Keywords:
Ultrasonography;
Breast neoplasms;
Metaplastic carcinoma;
Squamous cell carcinoma;
Pathology
- From:
Chinese Journal of Medical Imaging Technology
2017;33(3):410-413
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the ultrasonographic and pathological features of metaplastic carcinoma with squamous cell component (MCSC) of the breast.Methods The ultrasonographic and pathological features of 7 patients with breast MCSC confirmed pathologically were retrospectively analyzed.Results Seven cases were single lesion and the maximal diameters of the lesions were 2.6-5.1 cm.On two-dimensional imaging,6 lesions with cystic and solid were complex echogenic,only 1 lesion was hypoechoic.All the lesions had irregular shape (lobulated)and indistinct margin.On CDFI imaging,most of lesions had rich blood flow signals with high resistance (resistance index 0.75-0.91),4 lesions were grade l,2 lesions were grade Ⅱ and 1 lesion was grade Ⅰ blood flow signals.On gross histopathological examination,6 masses had cystic cavity,only 1 mass was pure solid.On microscopic histopathological examination,5 masses were adenosqua mous carcinoma,only 2 masses were pure squamous cell carcinoma.Estrogen receptors,progesterone receptors and human epidermal growth factor receptor were negative in 4 masses (triple-negative breast cancer).Conclusion MCSC have some distinguished ultrasonic characteristics of larger volume,cystic-solid mixed echo,posterior echo enhancement,abundant vascularity with high resistance.
