Analysis of reperfusion delay in patients with acute ST elevated myocardial infarction based on gender difference
10.11855/j.issn.0577-7402.2017.02.10
- VernacularTitle:性别对急性ST段抬高型心肌梗死患者再灌注时间延迟的影响
- Author:
Zhong ZHANG
;
Bei ZHAO
;
Tengfei WEI
;
Peiling LIU
;
Lifeng LIU
;
Li LIU
;
Jingtao ZHAO
;
Quanxing SHI
;
Zhao YIN
;
Mengmeng RAO
;
Shuai MAO
;
Shouli WANG
- Keywords:
myocardial infarction;
sex factors;
reperfusion delay
- From:
Medical Journal of Chinese People's Liberation Army
2017;42(2):144-148
- CountryChina
- Language:Chinese
-
Abstract:
Objective To examine the influence of gender difference on the reperfusion delay in patients with ST-elevation myocardial infarction (STEMI).Methods A total of consecutive 325 patients with STEMI were analyzed admitted in the 306 Hospital of PLA from Jan.2011 to Dec.2015.Patients were divided into two groups:male group (n=268) and female group (n=57).The clinical data and the time intervals including symptom onset to first medical contact (So-to-FMC),transfer delay (FMC-to-D),FMC to balloon dilatation (FMC-to-B),activation delay and door to balloon (D-to-B) time were compared between different gender groups,and the prognosis was observed.Results The overall median of pre-hospital delay was 125 minutes.The median of prehospital delay time (male 119.5min vs.female 160.0min) and So-to-FMC time (male 69.5min vs.female 100.0min) were longer in female than in male patients,but no statistical difference existed (P＞0.05) between the two groups in pre-hospital delay,So-to-FMC,FMC-to-B,D-to-B and total ischemia time.Compared with male patients,female patients were more likely to have additional comorbidities,such as hypertension and diabetes mellitus,and lower rate of smoking (P＜0.05).However,the incidence of major adverse cardiac and cerebrovascular events (MACCE) showed no significant difference between female and male patients at 30-day (male 5.22％ vs.female 5.26％) and I-year (male 10.82％ vs.female 8.77％) follow-up (P＞0.05).Conclusion The influence of gender on reperfusion delay is gradually weakening.
