Pathological analysis of coronary artery thrombus in different ischemic time in patients with ST-segment elevation acute myocardial infarction
10.11855/j.issn.0577-7402.2017.02.11
- VernacularTitle:急性ST段抬高型心肌梗死不同缺血时间冠状动脉内血栓的病理分析
- Author:
Mengmeng RAO
;
Bei ZHAO
;
Peilin LIU
;
Xueyao FENG
;
Quanxing SHI
;
Zhong ZHANG
;
Hongyong SONG
;
Li LIU
;
Jingtao ZHAO
;
Tengfei WEI
;
Li ZHOU
;
Shouli WANG
- Keywords:
myocardial infarction;
ischemia time;
thrombosis;
suction;
thrombus pathological types
- From:
Medical Journal of Chinese People's Liberation Army
2017;42(2):149-153
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between ischemic time and thrombus types in patients with ST-segment elevation myocardial infarction (STEMI).Methods Eighty-two STEMI patients undergone emergency percutaneous coronary intervention (PCI) and coronary thrombus aspiration (CTA) from Sep.2012 to Apr.2016 were included and divided into 3 groups according to the ischemic time:≤4 hours (n=36),4-7 hours (n=30) and ＞7 hours (n=16).Visible aspirated thrombi were collected and separated into erythrocyte-rich type,platelet/fibrin-rich type and combined type thrombi by HE dying.The percentage difference of the 3 types thrombi was compared among the 3 groups.Results The percentage of platelet/fibrinrich type,erythrocyte-rich type and combined type thrombi in the 3 groups were as follows:in ≤4h group:61.1％(22/36),8.3％(3/36) and 30.6％(11/36),P=0.019;in 4-7h group:23.3％(7/30),10.0％(3/30) and 66.7％(20/30),P=0.012;and in ＞7h group:43.8％(7/16),12.5％(2/16) and 43.8％(7/16),P=0.913.For platelet/fibrin-rich type thrombi,the percentages in 3 periods were 61.1％(22/36),19.4％(7/36) and 19.4％(7/36),P=0.009;For combined type thrombi,the percentages in 3 periods were 28.9％(11/38),52.6％(20/38) and 18.4％(7/38),P=0.013;For erythrocyte-rich type thrombi,the percentages in 3 periods were 37.5％(3/8),37.5％(3/8) and 25.0％(2/8),P=0.895.Conclusions The types of intracoronary aspirated thrombi differ from various periods.Ischemia time may be an important predicted factor.
