Molecular genetics and prognosis of lung cancer in young patients: Research highlights
10.11855/j.issn.0577-7402.2017.03.01
- VernacularTitle:青年肺癌分子遗传学以及预后的研究进展
- Author:
Yong SONG
;
Xianhui PAN
- Keywords:
non-small cell lung cancer;
young;
age;
molecular genetics;
echinoderm microtubule associated protein like4-anaplastic lymphoma kinase;
epidermal growth factor receptor;
treatment;
prognosis
- From:
Medical Journal of Chinese People's Liberation Army
2017;42(3):181-185
- CountryChina
- Language:Chinese
-
Abstract:
Differed from the elderly patients with lung cancer,the younger patients with lung cancer,less than 50 years old,present unique clinical features.Recently,the incidence of lung cancer in young people has shown a rising trend,making the research on this field more valuable.At present,molecular targeted therapy is one of the most popular areas of non-small-cell lung cancer (NSCLC),and researches are focused on the epidermal growth factor receptor (EGFR) and echinoderm microtubule associated protein like4-anaplastic lymphoma kinase (EML4-ALK).In addition,the previous researches revealed the differences between the young and elderly patients with lung cancer on molecular genetics and prognosis,so the researches on prognostic factors for young patients with lung cancer are of great clinical significance.The present paper will focus on the aspects of pathogenesis,molecular genetics and prognosis in young patients with lung cancer.
