MR arterial-spin-labeling perfusion imaging in crossed cerebellar diaschisis in cerebral gliomas

Xiaoxue Liu; Zhiqiang Zhang; Jianrui LI; Qiang XU; Yifei Weng; Guangming LU

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MR arterial-spin-labeling perfusion imaging in crossed cerebellar diaschisis in cerebral gliomas

VernacularTitle:大脑胶质瘤交叉性小脑神经机能联系不能的MR动脉自旋标记灌注成像
Author: Xiaoxue LIU ; Zhiqiang ZHANG ; Jianrui LI ; Qiang XU ; Yifei WENG ; Guangming LU
Keywords: Crossed cerebellar diaschisis; Arterial spin labeling; Magnetic resonance imaging; Glioma
From: Chinese Journal of Medical Imaging Technology 2017;33(4):510-513
CountryChina
Language:Chinese
Abstract: Objective To explore crossed cerebellar diaschisis (CCD) in cerebral gliomas with three dimensional arterialspin-labeling (3D ASL) perfusion MRI.Methods The images of 31 patients with cerebral gliomas and 31 normal subjects were retrospectively analyzed.The cerebral blood flow (CBF) were measured with 3D ASL technology,and the asymmetry index (AI) of cerebellar hemispheric CBF value changes were calculated and compared in patients.And the relationship between the AI values of cerebellar hemispheric and the AI values of tumor region in cerebral hemispheric,tumor histological grade and size were investigated.Results Compared with tumor ipsilateral cerebellar hemisphere of supratentorial glioma,the CBF value of contralateral cerebellar hemisphere significantly reduced (t=5.04,P＜0.01),and the AI values of cerebellar hemispheric in patients obviously increased compared to normal subjects (t=4.13,P＜0.01).But there was no significant difference in the AI values of cerebellum between high grade and low grade gliomas (t=1.31,P＞0.05).In cerebral gliomas patients,there was no significant correlation between the AI values of cerebellar hemispheres and the AI values of cerebral hemisphere (tumor:r=-0.28;tumor parenchyma:r=-0.24;tumor plus edema:r=-0.19,all P＞0.05),and tumor size (r=0.18,P＞0.05).Conclusion Cerebral glioma can cause CCD phenomenon,and 3D ASL is able to quantitatively assess the degree of cerebellar hypoperfusion noninvasively.This phenomenon may not be associated with tumor histological grade,size and the AI values of cerebral hemispheric.