Research progress of renal tubular epithelial-to-mesenchymal transition
10.3760/cma.j.issn.1673-4408.2017.04.012
- VernacularTitle:肾小管上皮间质转化的研究进展
- Author:
Fang YU
- Keywords:
Epithelial-to-mesenchymal transition;
Renal interstitial fibrosis;
drug therapy
- From:
International Journal of Pediatrics
2017;44(4):267-269
- CountryChina
- Language:Chinese
-
Abstract:
Renal interstitial fibrosis represents the final common pathway of all chronic disease.The mechanism of renal interstitial fibrosis is very complex.It is not entirely clear now.The study found that epithelial-to-mesenchymal transition plays an important role in the renal interstitial fibrosis.Inhibition of epithelial-tomesenchymal transition may help to slow down the development and progression of renal interstitial fibrosis.The article mainly reviews the mechanism and treatment of epithelial-to-mesenchymal transition.
