Research advances on relationship between CXC chemokine ligand 10 and viral hepatitis
10.3760/cma.j.issn.1674-2397.2017.02.015
- VernacularTitle:CXC趋化因子配体10与病毒性肝炎的研究进展
- Author:
Guangyu TENG
;
Yinghui LIU
;
Zhen ZHEN
- Keywords:
Hepacivirus;
Chemokines,CXC;
Chemokine CXCL10;
Antiviral agents
- From:
Chinese Journal of Clinical Infectious Diseases
2017;10(2):154-160
- CountryChina
- Language:Chinese
-
Abstract:
In the progress of viral hepatitis, lymphocytes migrate and infiltrate liver tissues, which is relevant to antiviral therapy.However, the related mechanism is still poorly understood.In recent years,CXC chemokine ligand (CXCL)10 and its receptor CXCR3 have been extensively studied.The interaction between CXCL10 and CXCR3 would be a breakthrough point for study of the mechanism of viral hepatitis pathogenesis.This article reviews the research advances of CXCL10 in the progression of viral hepatitis and in the evaluation of antiviral therapy.
