Clinical survey of recurrent acute pancreatitis

Di Zhang; Yaping Liu; Hao Zhang; Yawei BI; Dan Wang; Honglei Guo; Xiangpeng Zeng; Teng Wang; Lei Xin; Lianghao HU; Maojin XU; Zhaoshen LI

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Clinical survey of recurrent acute pancreatitis

VernacularTitle:复发性急性胰腺炎的临床特征分析
Author: Di ZHANG ; Yaping LIU ; Hao ZHANG ; Yawei BI ; Dan WANG ; Honglei GUO ; Xiangpeng ZENG ; Teng WANG ; Lei XIN ; Lianghao HU ; Maojin XU ; Zhaoshen LI
Keywords: Pancreatitis; chronic; Recurrent acute pancreatitis; Disease attributes
From: Chinese Journal of Pancreatology 2017;17(2):88-92
CountryChina
Language:Chinese
Abstract: Objective To analyze the clinical features of recurrent acute pancreatitis (RAP).Methods The clinical data of patients diagnosed as RAP were collected in Changhai Hospital, the Second Military Medical University between January 2016 to July 2016, and chronic pancreatitis(CP) patients and RAP patients to matching, as control group.A prospective cohort study about the clinical features of RAP and CP was set.The survival analysis model was established by Kaplan-Meier′s method, to calculate the cumulative rate of RAP which progressed into CP.Results The morbidity of male patients was 69.0% in the RAP group(n=100) and 60% in the CP group(n=100).The average first onset age of RAP and CP was 38 and 21 years old, respectively;and the teenagers accounted for 12% and 38.6%.The incidence of diabetes was 49.5% and 9%;and the incidence of fatty diarrhea was 46.6% and 19% of the two groups.The cumulative incidence of CP was 2% within 1 year, 4.6% in 3 years, and 12.4% in 5 years.Conclusions Men has higher morbidity in both RAP group and CP group.RAP patients′ first onset age was older than that of CP.Teenagers had a low incidence in RAP group.The risk of diabetes and fatty diarrhea was lower in RAP group than CP group.A certain proportion of RAP patients can progress to CP.