Association of ApoB/A-1 ratio with type 2 diabetes mellitus in Chinese Han ethnic population:A cross-sectional study
10.3760/cma.j.issn.1000-6699.2017.04.010
- VernacularTitle:中国汉族人群载脂蛋白B/A-1比值与2型糖尿病的相关性:一项横断面研究
- Author:
Chang LIU
;
Yongming HE
;
Xiaojiao DU
;
Dongping CAI
;
Xiangjun YANG
- Keywords:
ApoB/A-1 ratio;
Diabetes mellitus;
type 2;
Cross-sectional study
- From:
Chinese Journal of Endocrinology and Metabolism
2017;33(4):321-325
- CountryChina
- Language:Chinese
-
Abstract:
In this cross-sectional study, consecutive Chinese Han ethnic inpatients in the Division of Cardiology, the First Affiliated Hospital of Soochow University from January 1, 2010 to December 31, 2013 were included. According to the exclusion criteria, 9 587 patients [1 604 with type 2 diabetes mellitus (T2DM) and 7 983 without T2DM]were obtained for final analysis. Logistic regression model was used to analyze the association of ApoB/A-1 ratio with T2DM and the possible interactions between ApoB/A-1 ratio and other risk factors. The results showed that the distribution of ApoB/A-1 ratio was positively skewed in Chinese Han ethic population. The median of ApoB/A-1 ratio of female was lower than that of male (0.68 vs 0.73,P<0.01). In all groups, the proportion of T2DM was increased with the raised ApoB/A-1 ratio. By the stratification analyses of sex, age, coronary artery disease, and the use of statins, ApoB/A-1 ratio was still correlated with T2DM. There existed significant interactions between ApoB/A-1 ratio and the smoking status or creatinine in T2DM.
