Next generation sequencing technologies in clinical virological detection
10.3760/cma.j.issn.1009-9158.2017.05.002
- VernacularTitle:下一代测序技术在临床病毒学检验中的应用
- Author:
Jin XU
;
Menghua XU
- Keywords:
Virology;
High-throughput nucleotide sequencing;
Genome,viral;
Quality control
- From:
Chinese Journal of Laboratory Medicine
2017;40(5):338-340
- CountryChina
- Language:Chinese
-
Abstract:
Next generation sequencing technologies,providing high speed and throughput that contribute greatly to DNA sequencing,have many applications in clinical virology,including identification of novel or unsuspected viruses,evaluation of human viromes,investigation of viral genetic diversity and evolution,monitoring of antiviral drug resistance,and analysis of virus-host interaction.Meanwhile,due to the complexity in bioinformatics data processing and lack of quality management standards,further efforts and explorations need to be put in the application and quality management of NGS in clinical laboratory.
