Role of microphthalmia-associated transcription factor in melanoma metastasis
10.3760/cma.j.issn.1673-422X.2017.04.010
- VernacularTitle:小眼畸形相关转录因子在黑色素瘤转移中的作用
- Author:
Yan HE
;
Jun TIE
;
Jun TANG
- Keywords:
Neoplasms metastasis;
Microphthalmia-associated transcription factor;
Melanoma
- From:
Journal of International Oncology
2017;44(4):281-283
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, the function of microphthalmia-associated transcription factor (MITF) is a hot field in melanoma.The abnormal expression of MITF is closely related to the occurrence and metastasis of melanoma.In addition, the down expression of MITF promotes its invasion.Studying the regulation of MITF and its related molecules and signaling pathways will let us further understand the molecule mechanism of malignant melanoma metastasis and provide help to exploit novel molecular targeted drug.
