Research progress of RRx-001 as a sensitizer for radiotherapy
10.11958/20170073
- VernacularTitle:RRx-001作为放射治疗增敏剂的研究进展
- Author:
Yang GAO
;
Cuihong YANG
;
Liping CHU
- Keywords:
tumor;
radiotherapy;
epigenesis;
genetic;
nitric oxide;
review;
RRx-001;
radiosensitizer;
epigenetic modification
- From:
Tianjin Medical Journal
2017;45(5):545-548
- CountryChina
- Language:Chinese
-
Abstract:
Radiotherapy is one of the most important methods to treat malignant tumors. Due to the presence of radiation resistance, the effect of radiotherapy is not entirely satisfactory. To alleviate radiation resistance and improve the radiotherapy effect, radiosensitizers have emerged. As a newly discovered radiosensitizer, RRx-001 has a good clinical application prospect. This paper reviewed the research progress of RRx-001 in source, safety, radiotherapy sensitizing activity and related mechanisms.