Research progress of HGF/c-MET signaling pathway inhibitors in anti-pancreatic cancer

VernacularTitle:HGF/c-MET信号通路抑制剂在抗胰腺癌中的研究进展
Author: Yinbiao QIAO ; Bo YANG
Keywords: Hepatocyte growth factor; Pancreatic neoplasms; Proto-oncogene proteins c-met
From: Journal of International Oncology 2017;44(4):304-306
CountryChina
Language:Chinese
Abstract: Pancreatic cancer is one of the most malignant tumors.Targeted therapy has become an important part of the treatment of pancreatic cancer.The signaling pathways such as hepatocyte growth factor/c-MET (HGF/c-MET) signaling pathway, inhibition of which may exerts an antitumor effect, play extremely important roles in the occurrence and development of pancreatic cancer.Therefore, the research of HGF/c-MET targeted inhibitors opens up a new avenue for treatment of pancreatic cancer.