Relationship between serum adiponectin concentration and insulin resistance in elderly pregnancy patients with gestational diabetes mellitus
10.3760/cma.j.issn.1674-6090.2017.02.014
- VernacularTitle:妊娠期糖尿病高龄产妇血清脂联素水平与胰岛素抵抗的相关性研究
- Author:
Jieli WU
;
Qinqin SUN
;
Wenshu CHEN
;
Feng XU
- Keywords:
Gestational diabetes mellitus;
Elderly pregnancy patients;
Adiponectin;
Visfatin;
Insulin resistance
- From:
Chinese Journal of Endocrine Surgery
2017;11(2):143-146
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between serum adiponectin (APN) concentration and insulin resistance(IR) in elderly pregnancy patients(GDM) with gestational diabetes mellitus.Methods Data of 120 cases of elderly pregnancy patients with gestational diabetes mellitus admitted from Jan.2011 to Dec.2016 were retrospective analyzed.The relationship between serum APN concentration and IR was assayed.Healthy subjects and normal pregnancy patients in our Department were taken as the control.Results The concentration of APN was lower while the CysC,BNP,IGF1,IGF2 and IGFIR were higher in elderly pregnancy patients with gestational diabetes mellitus than those in the control group with a significant difference (P<0.05).At the same time,Spearman analysis results showed that the serum APN was negatively related with IR while CysC,BNP,IGF1,IGF2 and IGFIR were positively related with IR (P<0.05).Conclusion Theserumconcentrationofadiponectin and visfatin were negatively related with insulin resistance in elderly pregnancy patients with GDM.