Advances in the research on application of KL-6 in the diagnosis and treatment of interstitial lung disease
10.11855/j.issn.0577-7402.2017.04.15
- VernacularTitle:KL-6在间质性肺疾病诊治中的研究进展
- Author:
Ranran WANG
;
Jian ZHU
;
Jianglin ZHANG
- Keywords:
interstitial lung disease;
KL-6;
diagnosis;
prognosis
- From:
Medical Journal of Chinese People's Liberation Army
2017;42(4):354-357
- CountryChina
- Language:Chinese
-
Abstract:
Interstitial lung disease represents a group of diffuse pulmonary diseases that mainly affects pulmonary mesenchyme and alveolar spaces,resulting in loss of alveolar-capillary functions.It is also a common complication or an important factor that influences the prognosis of rheumatoid arthritis,dermatomyositis,systemic sclerosis.Searching for the biomarkers for the early diagnosis of the disease and/or indicative of the activity of the condition has been a subject of active investigations.KL-6,expressed on type Ⅱ pneumocytes,is seen as the most promising biomarker for the diagnosis of the disease.This review summarizes the recent researches about the use of KL-6 in the diagnosis and treatment of interstitial lung disease.
