Confirming Indicators of Qualitative Results by Chromatography-mass Spectrome-try in Biological Samples
10.3969/j.issn.1004-5619.2017.02.016
- VernacularTitle:生物样品的色谱-质谱定性确认指标
- Author:
Shaodan LIU
;
Daming ZHANG
;
Wei ZHANG
;
Wenfang ZHANG
- Keywords:
forensic toxicology;
chrom atography;
m ass spectrom etry;
review;
quality control;
qualitative research;
confirm ing indicator;
biological sam ple
- From:Journal of Forensic Medicine
2017;33(2):181-188
- CountryChina
- Language:Chinese
-
Abstract:
B ecause of the exist of com plex m atrix, the confirm ing indicators of qualitative results for toxic substances in biological sam ples by chrom atography-m ass spectrom etry are different from that in non-biological sam ples. E ven in biological sam ples, the confirm ing indicators are different in various ap-plication areas. T his paper review s the sim ilarities and differences of confirm ing indicators for the ana-lyte in biological sam ples by chrom atography-m ass spectrom etry in the field of forensic toxicological analysis and other application areas. T hese confirm ing indicators include retention tim e (R T ), relative re-tention tim e (R R T ), signal to noise (S/N ), characteristic ions, relative abundance of characteristic ions, parent ion-daughter ion pair and abundance ratio of ion pair, etc.
