Concept and Pathophysiology of Post-polio Syndrome (review)
10.3969/j.issn.1006-9771.2017.05.001
- VernacularTitle:脊髓灰质炎后综合征的概念及病理生理机制
- Author:
Aimin ZHANG
;
Yuming WANG
;
Huiming GONG
;
Junyi ZHANG
;
Qing SUN
;
Ran ZHANG
;
Jing LI
- Keywords:
post-polio syndrome;
pathophysiology;
review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2017;23(5):497-500
- CountryChina
- Language:Chinese
-
Abstract:
Post-polio syndrome (PPS) is a syndrome after acute infection of poliovirus and sequelae of polio. The incidence of PPS is high, and more in old patients. The pathological features of PPS include chronic nerve damage affected muscles, result in fatigue, pain, breathing and sleep disorders, fall risk, and so on, which impair their health and quality of life. The hypotheses of pathogenesis of PPS in-clude over load of motor neurons, and the continuous existence of the poliovirus, etc. PPS is a stable neuromuscular disease progressing slowly.