Analysis of Clinical Features of Alprostadil Lipid-micro Injection from 159 Hospitals of China

VernacularTitle:我国159家医院前列地尔脂微球注射剂临床使用特征分析
Author: Hui WANG ; Zhengyue LIU ; Yi DING ; Zhangwei YANG
Keywords: Alprostadil lipid-micro injection; Average daily dose; Rational use of drug; Adjuvant drug
From: China Pharmacy 2017;28(14):1903-1907
CountryChina
Language:Chinese
Abstract: OBJECTIVE:To provide evidence for rational use and clinical monitoring of Alprostadil lipid-micro injection (Li-po-PGE1). METHODS:Adult inpatients receiving Lipo-PGE1 from hospital information system(HIS)of 159 hospitals were select-ed as research subject. Based on frequency statistics,population,clinical diagnosis,and average daily dose of Lipo-PGE1 were all studied. RESULTS:A total of 71687 adult inpatients were included,and the male was more than female,mostly aged 61-75. The hospitalization duration was 8-14 d(45.01%),most of patients were recovered(68.20%). Lipo-PGE1 was wildly used in the clin-ic,and was used for 871 kinds of clinical diseases in total;top 3 diseases were cerebral infarction(9.06%),non-insulin dependent diabetes mellitus (8.65%) and chronic ischemic heart disease (8.08%). The average daily dose of different diseases and different hospitals were significantly different,mostly≤12.5μg. CONCLUSIONS:As adjuvant drug,medical institutions and related super-vision departments should formulate reasonable monitoring index and strengthen medication guidance and evaluation of Lipo-PGE1.