Analysis on the influencing factors of renal dysfunction in people with type 2 diabetes mellitus
10.16462/j.cnki.zhjbkz.2017.09.013
- VernacularTitle:2型糖尿病人群肾功能异常影响因素分析
- Author:
Enchun PAN
;
Dandan MIAO
;
Qin ZHANG
;
Yu QIN
;
Zhongming SUN
;
Chuang WANG
;
Ming WU
- Keywords:
Diabetes mellitus,type 2;
Risk factors;
Multivariate analysis
- From:
Chinese Journal of Disease Control & Prevention
2017;21(9):913-916,920
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the status of renal function abnormalities and explore its influencing factors in a community-based population with type 2 diabetes mellitus (T2DM).Methods Totally 9 413 patients with T2DM who have registered and received management of community public health service in 2014 were recruited in our study.All participants undertook questionnaire survey,physical examination and laboratory test.A simplified MDRD formula was used for estimating Glomerular Filtration Rate (eGFR),and Logistic Regression method was used to analyze the risk factors.Results The average eGFR was 91 ml/min · 1.73 m2 and the attack rate of people with eGFR ＜60 ml/min 1.73 m2 was 10.56％.The difference of renal function in participants with different age and gender was significant(x2 =6.306,P =0.012;x2 =269.293,P ＜ 0.001).Renal function in male patients and older patients was more worse.Multivariate analysis showed that long duration of diabetes,high levels of low density lipoprotein (LDL),total cholesterol (TC) and triglycerides (TG),uncontrolled blood glucose were independent risk factors for renal dysfunction.Conclusions Patients with T2DM are susceptible to renal function abnormalities.Comprehensively control of blood glucose,blood lipid and blood pressure should be performed to decrease the risk of the disease.
