Advances in Study on Relationship Between LncRNA and Inflammatory Diseases
10.3969/j.issn.1008-7125.2017.09.012
- VernacularTitle:LncRNA与炎症性疾病关系的研究进展
- Author:
Xinyu PEI
;
Zonghao CHEN
;
Yu ZHOU
- Keywords:
Inflammatory Disease;
Long Non-Coding RNA;
Inflammation;
Inflammatory Bowel Diseases
- From:
Chinese Journal of Gastroenterology
2017;22(9):565-568
- CountryChina
- Language:Chinese
-
Abstract:
Long non-coding RNA (lncRNA)is a non-coding RNA which lacks a complete open reading frame (ORF)and plays an important role in biological processes such as cell proliferation,differentiation and apoptosis. At present,expression of lncRNA has been found to be abnormal in inflammatory reaction and inflammatory diseases. It might be involved in the development and progression of inflammatory diseases via regulating the expression of multiple genes and activation of signaling pathways. This article reviewed the progress in study on relationship between lncRNA and inflammatory diseases.