Coronary CTA combined CT myocardial perfusion imaging in diagnosis of coronary artery disease:Meta-analysis
10.13929/j.1003-3289.201612117
- VernacularTitle:冠状动脉CTA联合CT心肌灌注成像诊断冠心病:Meta分析
- Author:
Xiangyi CAI
;
Honglin LI
;
Xueqin GUAN
;
Jin FANG
;
Quan ZHOU
- Keywords:
Coronary artery disease;
Tomography,X-ray computed;
Angiography;
Perfusion imaging;
Meta-analysis
- From:
Chinese Journal of Medical Imaging Technology
2017;33(9):1344-1348
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the diagnostic value of coronary CTA (CCTA) combined myocardial CT perfusion imaging (CTP) in coronary artery disease (CAD) with Meta-analysis.Methods Chinese and English literatures evaluating CCTA combined CTP in diagnosis of CAD in PubMed,Wed of Science,Cochrane Library,China National Knowledge Infrastructure (CNKI) and Wanfang Periodical Database from inception to December 2016 were searched.The extraction was conducted according to the criteria for diagnostic recommended by Cochrane Method Group.The quality of included studies was assessed with quality assessment of diagnostic accuracy studies-2 instrument.The statistical analysis was performed by Meta-disc 1.4 software,the diagnosis efficacy was calculated and the symmetric receiver operating characteristic curves (SROC) was drawn to obtain the area under curve (AUC).Results Five studies involving a total of 611 vessels were included.The pooled sensitivity (SEN),specificity (SPE),diagnostic odds ratio (DOR),positive likelihood ratio (PLR),negative likelihood ratio (NLR) were 0.96 (95％CI [0.92,0.98]),0.91 (95％CI [0.88,0.94],206.14 (95％CI [100,424.94]),9.33 (95％CI [5.57,15.61]),0.06 (95％CI [0.03,0.13]),respectively.The AUC of SROC was 0.977.Conclusion CCTA combined CTP has significant value in diagnosis of CAD.
