Advances in therapeutic options for peripheral T-cell lymphomas

VernacularTitle:外周T细胞淋巴瘤临床治疗进展
Author: Zheng WU ; Suyu ZHU
Keywords: T-cell lymphomas; Treatment; Prognosis
From: Chinese Journal of Radiation Oncology 2017;26(5):588-592
CountryChina
Language:Chinese
Abstract: Peripheral T-cell lymphoma (PTCL) is a highly specific and invasive non-Hodgkin's lymphoma derived from mature T-cells that leave the thymus.At present, the clinical progress in PTCLs is behind that in B-cell lymphomas, and the current treatments for PTCLs have low efficacy and poor overall prognosis.Therefore, there is currently still no standard treatment for PTCL.The efficacy of the conventional CHOP chemotherapy regimen is poor, and the value of radiotherapy in early-stage PTLC patients remains to be determined.Autologous hematopoietic stem cell transplantation is the top choice for consolidation treatment for high-risk patients, but the efficacy of novel drugs for PTCLs needs to be further confirmed.In addition, PET/CT plays a more important role in predicting the prognosis of PTCLs.