Correlation of Traditional Chinese Medicine Syndrome Types of Hypertension with Carotid Artery Intima-media Thickness and Plasma Lp-PLA2 Expression
10.13359/j.cnki.gzxbtcm.2017.03.004
- VernacularTitle:高血压病中医证型与颈动脉内—中膜厚度及血浆Lp-PLA2表达的相关性研究
- Author:
Miaofen HUANG
;
Huiwen XIE
- Keywords:
hypertension;
traditional Chinese medicine(TCM) syndrome types;
carotid artery atherosclerosis;
lipoprotein-associated phospholipase A2 (Lp-PLA2)
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2017;34(3):317-320
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the correlation of traditional Chinese medicine (TCM) syndrome types of hypertension with carotid artery intima-media thickness (IMT) and plasma lipoprotein-associated phospholipase A2 (Lp-PLA2),so as to provide a TCM therapy for early prevention and treatment of hypertension and its complications in clinic.Methods We collected a total of 170 cases of hypertension patients,55 with kidney-essence insufficiency syndrome,50 with ascendant hyperactivity of liver yang syndrome,and 65 with phlegm-damp retention in middle energizer syndrome.IMT was measured by the carotid Doppler ultrasound,and plasma Lp-PLA2 expression was examined by enzyme-linked immunosorbent assay.And then the differences of IMT and Lp-PLA2 expression among the three groups were compared and analyzed.Results There were significant differences of carotid artery IMT and Lp-PLA2 among the three groups(P＜ 0.01),and the number of patients with carotid atherosclerosis and the expression level of Lp-PLA2 in the group of phlegm-damp retention in middle energizer syndrome were higher than those intheothertwogroups(P＜0.01).Conclusion Differentiation treatment based on phlegm may be more conducive to the prevention and treatment of hypertension and its complications.
