CEUS in dynamicly assessing blood perfusion of hepatic alveolar echinococcosis in rats
10.13929/j.1672-8475.201703026
- VernacularTitle:CEUS评价大鼠肝泡状棘球蚴病灶血流灌注的动态演变
- Author:
Hongchun ZENG
;
Yingxin WANG
;
Junhua WANG
;
Wei HAN
;
Wenya LIU
- Keywords:
Alveolar echinococcosis;
Liver;
Ultrasonography
- From:
Chinese Journal of Interventional Imaging and Therapy
2017;14(9):566-570
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value of CEUS in dynamicly assessing the blood perfusion of hepatic alveolar echinococcosis (HAE) in rats.Methods The experimentally induced secondary HAE in totally 70 rats were studied at different time periods (gth week,28th week,and 50th week) with CEUS,and compared to pathology results.Results At the 9th week,55 HAE lesions (55/70,78.57％) presented hyperechoic and the rest of 15 HAE lesions (15/70,21.43％)presented mixed echogenicity.The single or multiple vesicular structures were found as pathological feature.At later stages (28th week and 50th week),the size of lesions increased compared to 9th week with more solid structures and the calcifications found in HAE lesions.Microscopically,the fibrous tissues surrounding the lesions gradually thickened and the microvascular accumulation were visible around the lesions.The HAE lesions at the 9th week showed the ring enhancement and central septa enhancement in CEUS.The HAE lesions at the 28th week and 50th week showed combinations of no enhancement,ring enhancement,and central septa enhancement in CEUS.The ratio of edge enhancement to maximum diameter of lesions decreased with the progression (P=0.02).Conclusion The ultrasonographic features in HAE lesions become more complicated with increasing calcifications and enlarged necrosis areas with the progression.The CEUS can reveal the dynamics of blood perfusion of HAE lesions at different stages.
