Investigation of irregular antibodies in blood samples from donors in Shanghai area
10.13303/j.cjbt.issn.1004-549x.2017.07.049
- VernacularTitle:上海地区无偿献血者血液中不规则抗体的调查
- Author:
Yin CAI
;
Bin CAO
;
Zhe ZHOU
;
Zhongying WANG
;
Li WANG
;
Lan ZHENG
;
Guoping ZHOU
- Keywords:
Irregular antibody;
Blood donor;
Microplate Papain method;
Saline medium
- From:
Chinese Journal of Blood Transfusion
2017;30(7):791-793
- CountryChina
- Language:Chinese
-
Abstract:
Objective With the purpose of further improving blood safety and providing the reference basis for a strategy suitable for large-scale routine screening of irregular antibodies in blood service,the irregular antibodies in blood samples from donors in Shanghai area were investigated.Method Irregular blood antibodies were screened in 824 072 blood donors through combined method of saline medium and microplate papain.Result 1 246 samples of blood donors were detected with irregular antibodies among the total 824 072 samples which indicate the positive rate of 1.51‰.Conclusion Screening of irregular antibodies in blood samples from donors can effectively reduce or avoid hemolytic transfusion reactions.The combined method of saline medium and microplate papain is an effective method for large-scale routine screening of irregular antibodies in blood service.
