The Primary Study on the Methods and Feasibility of Re-entry of NAT Reactive Blood Donors
10.13303/j.cjbt.issn.1004-549x.2017.07.060
- VernacularTitle:核酸检测反应性献血者归队方法学及可行性的初步研究
- Author:
Yana REN
;
Guoping ZHOU
;
Zhongying WANG
;
Yinren ZHANG
;
Qinying ZHAO
;
Kaicheng QIAN
- Keywords:
NAT reactive;
re-entry of blood donors;
ECLA
- From:
Chinese Journal of Blood Transfusion
2017;30(7):818-821
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the methods andfeasibility of re-entry of NAT reactive blood donors.Methods ELISA Non-Reactive(NR) and NAT Reactive(R) Blood Donors in 2012-2014 were selected and informed consent.Blood samples collected were tested:ELISA (HBsAg、Anti-HCV、Anti-HIV and Anti-TP) and NAT (HBV-DNA、HCV-RNA and HIVRNA).ELISA NR/NAT NR samples were tested by ECLA for HBsAg、HBeAg、Anti-HBs、Anti-HBc、Anti-HBe、Anti-HCV、Anti-HIV.Results 30 donors were called back,and 11 of them were ELISA NR/NAT R,which were deferred permanently.19 of them were ELISA NR/NAT NR,and the ECLA results were 89.5％ ELISA NR/NAT NR donors were Anti-HBc R and/or Anti-HBe R (12 cases Anti-HBc/Anti-HBe R、5 cases Anti-HBe R).Anti-HBc R or Anti-HBe R donors had risk of infection,which were deferred permanently.2 cases all items Non-Reactive may be eligible for re-entry.Conclusion Re-entry of NAT reactive blood donors is very necessary and meaningful,but in the view of blood safety,it is important that establish a set of safe program for Chinese.
