Establishment of Quality Standard System for Gui Erbai Gel Based on a Method of A System to Multiple Evaluation
10.3969/j.issn.1008-049X.2017.09.011
- VernacularTitle:"基于""一体多评""法建立鬼二白凝胶的质量标准体系"
- Author:
Xianshun XU
;
Hongen QIN
;
Sibo ZHANG
;
Yongfang XIA
;
Lei PENG
;
Yuancui XU
- Keywords:
Gui Erbai gel;
A system to multiple evaluation;
Quality standard
- From:
China Pharmacist
2017;20(9):1559-1563
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish the quality standard system of Gui Erbai gel based on a method ofa system to multiple evalu-ation and discuss the feasibility of the method used for the quality standard for traditional Chinese medicine. Methods:TLC identifi-cation of Gui Erbai gel was established by one thin layer system. An HPLC method was used to detect 6 active components in Gui Erbai gel. Results:Five active components in the gel could be identified by one thin layers system simultaneously with clear spots and good separation. Six active components in the gel could be determined by the same HPLC system with high accuracy. The average content of podophylotoxin,quercetin,kaempferol,imperatorin,dictamnine and rutin is as follows 0. 154,0. 052,0. 138,0. 051,0. 060,0. 048 mg· g-1 . RSD<3％. Conclusion:The established method based on a system to multiple evaluation can be used for the quality standard establishment for Gui Erbai gel with the properties of promising feasibility, simple operation, low cost, high accuracy and good stabili-ty.
