Compatible Stability of Xiaoaiping Injection and Insulin in Glucose Infusion
10.3969/j.issn.1008-049X.2017.09.040
- VernacularTitle:消癌平注射液与胰岛素在葡萄糖注射液中的配伍稳定性考察
- Author:
Wen PENG
;
Yaohua WANG
;
Jukun JIA
;
Zhiqiang SUN
;
Dongxiao SUN
;
Yan MENG
;
Xiaohua REN
- Keywords:
Xiaoaiping injection;
Insulin;
Stability;
Compatibility
- From:
China Pharmacist
2017;20(9):1665-1667
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the compatibility of Xiaoaiping injection and insulin for injection in glucose infusion. Methods:The changes in appearance, particles and pH of the mixture in 24h at ambient temperature were observed. The concentration of chloro-genic acid and insulin were determined by HPLC. Results:There were no obvious changes in appearance, pH, precipitation or turbidi-ty generation, and the contents of insulin and chlorogenic acid kept stable in 12 h. The number of insoluble particles was stable in 12 h, and then gradually increased in 24 h. Conclusion:Xiaoaiping injection and insulin in 5％ glucose infusion is stable in 12h under the testing conditions.
