Comparing the differences between domestic and imported EIA-HIV screening results for voluntary blood donors
10.13303/j.cjbt.issn.1004-549x.2017.07.058
- VernacularTitle:比较分析国产与进口两种HIV酶免试剂对无偿献血者筛查结果的差异性
- Author:
Liqiang XU
;
Xiuwen NI
;
Jianhua LI
;
Jianqi SUN
;
Huina MAO
- Keywords:
HIV1/2;
EIA;
voluntary blood donors;
western blot (WB)
- From:
Chinese Journal of Blood Transfusion
2017;30(7):813-815
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the differences of two kinds of EIA reagents for HIV-1/2 (Ab/Ag) screening results of voluntary blood donors,in addition to find out the feasibility of reducing 1 times of EIA detection.Methods To collect data of HIV 1/2 screening positive results and confirmatory test for voluntary blood donors from 2009 to 2014 in Jiaxing area,and to compare the relationship of screeing test results with that of the confirmatory test,and then to analyze the relevance between S/CO values of screening test and confirmatory test.Results Screening positive rates of domestic and imported reagents,which were 9.58/10 000 and 12.43/10 000,respectively;and the confirmatory coincidence rates were 11.84％ and 9.12％,respectively.There was no significant difference (x2 =1.11,P＞0.05).The double-reagent joint detection positive rate was 1.37/10 000,and its positive predictive value was 82.86％.Single-reagent test result compared with that of double-reagent test,which had significant differences (x2domestic =94.04,P＜0.05 and x2ximported =124.86,P＜0.05).When the S/CO value was more than 6,domestic and imported reagents positive predictive values were 93.55％ (29/31) and 87.50％ (28/32),respectively.Conclusion There is no difference between domestic and imported reagents EIA-HIV1/2.
