Extraction Optimization of Qishan Sugar-free Granule by Orthogonal Design
10.3969/j.issn.1008-049X.2017.09.009
- VernacularTitle:芪山无糖颗粒剂的提取工艺优化
- Author:
Zhilian XU
;
Yuzhi HONG
- Keywords:
Orthogonal design;
Extraction technology;
Total flavones;
Baicalin;
Berberine hydrochloride
- From:
China Pharmacist
2017;20(9):1550-1553
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the best extraction technology of Qishan sugar-free granule. Methods:The effects of boiling dura-tion, boiling times and water addition ratio on the extraction process were investigated by using L9 (34 ) orthogonal design, and the con-tents of total flavonoids, baicalin and berberine were taken as the indices. Results:The optimum conditions were as follows:10-fold a-mount of water for 2 cycles, and every extracting time was 1 hour. Conclusion: The best extraction technology of Qishan sugar-free granule is obtained, and the process is stable and feasible, and the contents of active components are high.
