What the results of Acarbose Cardiovascular Evaluation(ACE) Study will be?

VernacularTitle:对阿卡波糖心血管评估(ACE)研究结果的预测
Author: Yongquan SHI ; Yan LI
Keywords: Acarbose; Prediabetes; Cardiovascular outcome
From: Chinese Journal of Endocrinology and Metabolism 2017;33(8):705-708
CountryChina
Language:Chinese
Abstract: The prevalence of prediabetes is increasing rapidly in China, and with higher prevalence in coronary heart disease and hypertension patients. Diabetes can be controlled and prevented, previous studies have confirmed that lifestyle interventions and drug interventions can delay the progression of prediabetes to diabetes, and acarbose can be used for the primary prevention of cardiovascular events in impaired glucose tolerance(IGT) and diabetic patients, but benefits of drug intervention for secondary prevention of cardiovascular disease in IGT population are uncertain. The Acarbose Cardiovascular Evaluation(ACE) Study is a multicentre, randomized, placebo-controlled, double-blind study, with the aim of assessing the use of acarbose to reduce the risk of cardiovascular events and the onset of diabetes in IGT patients with cardiovascular disease in China , the results will be very meaningful and valuable for the prevention and treatment of diabetes. We will predict the results of ACE Study based on previous evidences.