Effect of sedation on respiratory function of patients undergoing mechanical ventilation

VernacularTitle:镇静对机械通气患者呼吸功能的影响
Author: Jie YANG ; Yan KANG
Keywords: Sedation; Mechanical ventilation; Respiratory function
From: Chinese Critical Care Medicine 2017;29(9):857-860
CountryChina
Language:Chinese
Abstract: Sedation and analgesia for ventilated patients is an important treatment in intensive care unit (ICU). Patients receiving mechanical ventilation therapy comfortably and safely can improve patient-ventilator synchrony, reduce ventilation-related lung injury (VILI), improve compliance, decrease oxygen consumption and stress, prevent accidents, and reduce the incidence of complications and mortality in critical patients. Although sedation mayprotect lung function, it also has a greater impact on respiratory function. Therefore, based on domestic and overseas related researches about sedation therapy in ventilated patients, we expounded on the effects of sedation therapy, different sedatives and different sedative methods on respiratory function of ventilated patients. The effects of sedation improving patient-ventilator synchrony or protecting pulmonary function as well as problems about inhibition of spontaneous respiration or delayed extubation were discussed to provide references for sedation treatment in patients with mechanical ventilation.