Research progress on necrotizing enterocolitis
10.3760/cma.j.issn.1673-4912.2017.08.011
- VernacularTitle:新生儿坏死性小肠结肠炎的研究进展
- Author:
Qian WANG
- Keywords:
Necrotizing enterocolitis;
Risk factors;
Outcome;
Prevention and treatment
- From:
Chinese Pediatric Emergency Medicine
2017;24(8):610-615
- CountryChina
- Language:Chinese
-
Abstract:
Necrotizing enterocolitis (NEC) is one of the common critical disease in preterm infants,not only the mortality is high,but part of the surviviors suffer from complications,such as intestinal stenosis,intestinal obstruction,malnutrition,parenteral nutrition associated cholestasis,and even short bowel syndrome,intestinal function failure and neurological dysfunction.The etiology of NEC is complex and the pathogenesis has not yet entirely clear.Therefore,early diagnosis of NEC is more difficult.In recent years,premature birth,unreasonable feeding,Toll-like receptors expression,bacterial colonization,hypoxia ischemia and hemodynamic changes are considered to be the risk factors of NEC.However,breast feeding and probiotics can reduce the incidence of NEC in premature infants.
