Study on expression of serum tumor markers spectrum and chemokine protein in lung cancer and its predictive value
10.3969/j.issn.1671-8348.2017.25.009
- VernacularTitle:血清肿瘤标志物谱及趋化因子蛋白在肺癌中的表达及预测价值研究
- Author:
Nan ZHANG
;
Tiejun LI
;
Kunpeng LI
;
Chuanmeng BAI
;
Jiwu ZHOU
;
Zengren ZHAO
- Keywords:
lung neoplasms;
gastrin-releasing peptide;
carcinoembryonic antigen
- From:
Chongqing Medicine
2017;46(25):3484-3485,3488
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the expression and predictive value of serum tumor markers spectrum and chemokine protein in lung cancer and predictive value.Methods One hundred and fifty patients with lung cancer were selected as the observation group and contemporaneous 150 individuals undergoing physical examination served the control group.The levels of ProGRP,CEA,SCC and Cyfra21-1 were measured by chemiluminescence microparticle immunoassay.The chemokine protein was determined by multiple immunofluorescent assay.Results The levels of CCL28,LIF,LIGHT and GRO in the observation group were significantly higher than those in the control group (P＜0.05).The levels of CCL28,LIF,LIGHT and GRO in the observation group were higher than those in the control group.The levels of CCL28,NAP-2 and MDC in the observation group were lower than those in the control group (P＜0.05).Conclusion The regular detection of serum tumor markers spectrum and chemokine protein can predict the treatment prognosis and evaluate the clinical curative effect.
