Therapeutic effect of endoscopic retrograde biliary drainage and nasal biliary drainage for hilar cholangiocarcinoma
10.3760/cma.j.issn.1007-5232.2017.07.003
- VernacularTitle:内镜下胆道支架植入及鼻胆管引流对肝门部胆管癌的治疗效果
- Author:
Yuting LI
;
Yifan LIN
;
Yang LIU
;
Wenyan GAO
;
Zhuo YANG
;
Yingchun ZHANG
;
Chunhong LEI
;
Tianjiao SHENG
;
Zhuolin WU
;
Danyang CUI
;
Li YU
;
Yang GONG
- Keywords:
Bile duct neoplasms;
Endoscopy;
Hilar cholangiocarcinoma;
Biliary stent;
Nasal biliary drainage
- From:
Chinese Journal of Digestive Endoscopy
2017;34(7):466-469
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical effect of endoscopic retrograde biliary drainage (ERBD) and endoscopic naso-biliary drainage (ENBD) on hilar cholangiocarcinoma (HACC).Methods The clinical data of 87 patients with HACC,who underwent ERBD and ENBD form January 2010 to January 2016,were retrospectively analyzed.The incidence of postoperative severe cholangitis,biliary obstruction again within 4 weeks,reduction of total bilirubin and survival time were studied.Results There were significant differences between ERBD group and ENBD group on the incidence of severe cholangitis[29.2％ (14/48) VS 10.3％ (4/39),x2 =4.689,P=0.030] and bile duct obstruction in 4 weeks after operation [47.9％ (23/48) VS 23.1％ (9/39),x2=5.710,P =0.017].The total bilirubin within 2 weeks and 4 weeks postoperatively was significantly reduced compared with that before operation (P＜0.05).There was no statistical difference in descend range of total bilirubin between the two groups.There was significant difference between ERBD group and ENBD group in the median survival time [14 weeks (range,0-60 weeks) VS 34 weeks (range,2-96 weeks),x2 =10.101,P=0.010].Conclusion Compared to ERBD,ENBD has certain advantages on palliative care for HACC.
