Microbial Transformation of Glycosides in Chinese Herbal Medicine
10.11842/wst.2017.05.025
- VernacularTitle:微生物发酵技术在中药苷类生物转化中的应用进展
- Author:
Zongmin MA
;
Xuhong DUAN
;
Meng QIN
;
Luqi HUANG
;
Lin PEI
- Keywords:
Glycoside;
aglycon;
Chinese herbal medicine;
microbial transformation
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2017;19(5):858-864
- CountryChina
- Language:Chinese
-
Abstract:
Glycosides are the active ingredients (AIs) of many Chinese herbs and have become hot spots along with the findings of their new functions,such as anti-inflammatory,antivirus,enhanced immunity and anti-cancer.It has been found that glycosides exert their effects by converting to aglycons or other AIs in vivo.Therefore,the transformation of glycosides to the corresponding AIs in vitro becomes very important to enhance their bioavailabilities.The microbial transformation has an unparalleled advantage in the transformation of Chinese herbs in vitro for its reaction specificity,less by-products,mild reaction conditions and environmental protection.This paper summarized and prospected researches of glycosides' microbial transformation.
