Study on Medication Rules of Chinese Herbal Medicine Compound in Primary Dysmenorrhea Treatment Based on Data Mining
10.11842/wst.2017.05.003
- VernacularTitle:基于数据挖掘中药复方治疗原发性痛经用药规律探索
- Author:
Haoyang ZHANG
;
Lijian PANG
;
Chuang LIU
;
Jia XU
;
Xiaodong LV
- Keywords:
Chinese herbal medicine compound;
primary dysmenorrhea;
data mining;
frequency analysis;
cluster analysis;
association rules analysis;
rule;
mechanism
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2017;19(5):733-739
- CountryChina
- Language:Chinese
-
Abstract:
This study was aimed to explore the medication rules of Chinese herbal medicine compound in the treatment of primary dysmenorrheal based on data mining.Relevant literatures on Chinese herbal medicine compound in the treatment of primary dysmenorrhea were retrieved from June 2006 to June 2016 in the Chinese Journal Full-text Database (CNKI) to establish a literature database.The Excel 2010,SPSS 22.0 and SPSS Modeler 14.2 software were used in the frequency analysis,cluster analysis,association analysis,and etc.The results showed that literatures related to Chinese herbal medicine compound in the treatment of primary dysmenorrhea,there were 74 compound formula and 76 kinds of Chinese herbal medicine involved.Angelica was the core single Chinese herbal medicine.Chinese herbal medicine with high-frequency usage was the type of removing blood stasis,invigorating qi and blood.Cluster analysis can form 5 clustering combination.Primary dysmenorrhea was mainly clustered to two syndromes,which were qi and blood deficiency with blood stasis,liver and kidney deficiency with qi stagnation and blood stasis.The association rules analysis showed that there were a total of 25 rules,with the most common combination of two or multiple combination from four kinds of Chinese herbal medicine,including Angelica,Radix Paeoniae Alba,Rhizoma Chuanxiong,and Rhizoma Corydalis.It was concluded that blood stasis was the direct cause of primary dysmenorrhea,many of which belonged to the deficiency of root (i.e.,deficiency of qi,blood and cold deficiency) and excess of branch.Chinese herbal medicine treatment should be focused on the regulation of both qi and blood,invigoration of both liver and kidney,as well as harmonization of the blood.
