Effects of galactooligosaccharide on the intestinal flora in premature rats
10.3969/j.issn.1671-8348.2017.08.003
- VernacularTitle:低聚半乳糖对早产大鼠肠道菌群的调节作用
- Author:
Yuandong CHEN
;
Hongyan LU
;
Ming CHANG
;
Jiyan SHAN
- Keywords:
galacto oligosaccharide;
preterm rats;
intestinal flora
- From:
Chongqing Medicine
2017;46(8):1015-1016,1019
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effects of galactooligosaccharide on the intestinal flora in premature rats.Methods Premature Sprague-Dawley rats were randomly divided into GOS group and control group.Premature rats in GOS group were feeding with GOS according 4 g/kg by dropper for 14 d.At 7 d and 14 d after feeding,the mental state and weight of rats were observed and recorded,the fresh feces in terminal rectum were collected to culture and count the number of colonies of bifidobacteria,lactobacillus,enterobacteria and enterococcus.Results Rats in GOS and the control group were normal growth during the administration period,mental state was not abnormal.Compared with the same time point of the control group,there was no significant difference in weight gain between the GOS group(P＞0.05).After feeding GOS for 7 d,there was no statistically significant difference between the number of colonies of bifidobacteria,lactobacillus,enterobacteri.a and enterococcus (P＞0.05).After feeding GOS for 14 d,the number of colonies of bifidobacteria and lactobacillus increased significantly(P＜0.05),while the number of enterobacteria and enterococcus decreased significantly (P ＜ 0.05).Conclusion Galactooligosaccharide could promote the proliferation of bifidobacterium and lactobacillus,inhibit the growth and reproduction of enterobacteria and enterococcus,so regulate the balance of intestinal flora.
