The study on the change of serum levels of soL-CXCL16 and NT-proBNP in patients with percutaneous coronary stenting following PCI
10.3969/j.issn.1671-8348.2017.08.009
- VernacularTitle:急性心肌梗死患者经皮冠状动脉支架植入术术后血清soL-CXCL16及NT-proBNP水平变化分析
- Author:
Li CAO
;
Dongmei AN
;
Lei SHI
;
Gangjun ZONG
- Keywords:
peri-percutaneous coronary intervention;
soluble chemokine 16;
NT-proBNP
- From:
Chongqing Medicine
2017;46(8):1036-1037,1041
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical value of the variety of serum levels of soL-CXCL16 and NT-proBNP peripercutaneous coronary intervention(PCI) in patients with acute myocardial infarction (AMI).Methods A total of 77 cases received PCI were selected to research group.And the contemporaneous 30 healthy persons were chosen to control group.The serum levels of soL-CXCL16,NT-proBNP and cTnT were detected by ELISA.The relationships of soL-CXCL16 and NT-proBNP to cTnT were detected by Pearson linear correlation analysis.Results Compared to pre-PCI,the serum levels of CXCL16 were rising to the peak point at 0.5 h post-PCI,and were decreasing from 2.0 h post-PCI,then the serum levels of CXCL16 were declining to the levels of pre-PCI at 24.0 h post-PCI (P＜0.05).And the serum levels of NT-proBNP were rising from 0.5 h post-PCI,and the peak point was at 24.0 h post-PCI (P＜0.05).The postive relationships of the serum levels of CXCL16 and NT-proBNP to the serum levels of cTnT were confirmed by Pearson linear correlation analysis(P＜0.01).Conclusion Monitoring of soL-CXCL16 and NT-proBNP for patients with percutaneous coronary stenting could provide foundation for prognosis evaluation of PCI.
