Clinical comparative study of patients with PI-IBS and NPI-IBS
10.3969/j.issn.1671-8348.2017.09.018
- VernacularTitle:PI-IBS与NPI-IBS患者的临床对比研究
- Author:
Xiaoping ZHANG
;
Hongfang PAN
;
Liang PAN
;
Lanlan XUN
- Keywords:
irritable bowel syndrome;
inflammatory induction;
cytokines;
gastrointestinal function
- From:
Chongqing Medicine
2017;46(9):1206-1207,1210
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical characteristics in the patients with post infectious irritable bowel syndrome(PI-IBS) and patients with non-PI-IBS(NPI-IBS).Methods Ninety-three patients with irritable bowel syndrome(IBS) treated in our hospital from March 2014 to June 2015 were selected,including 38 cases of PI-IBS and 55 cases of NPI-IBS.The differences of serum inflammatory cytokines levels,gastrointestinal score and gastrointestinal function were compared between the two groups.Resuits The levels of CRP,IL-18 and IL-6 in the PI-IBS group were significantly higher than those in the NPI-IBS group,and the difference was statistically significant (P＜0.05);the level of GAS,VIP and MOT in the PI-IBS group were significantly lower than those in the NPI-IBS group,the difference was statistically significant(P＜0.05);the bowel sounds score,abdominal distension and pain score and gastrointestinal reaction score in the PI-IBS group were obviously higher than those in the NPI-IBS group,the difference was statistical significance (P＜0.05);the various dimensional scores of quality of life in the PI-IBS group were lower than those in the NPI-IBS group,and the difference was statistically significant (P＜0.05).Conclusion The levels of serum inflammatory cytokines in PI-IBS patients are higher,moreover the gastrointestinal function is poorer than that in NPI-IBS patients,which can be the indicators of clinical differentiation.
