Effects of Electroacupuncture at ST36 on Levels of Gastrointestinal Hormone Motilin and Gastrin in FGIDs-D Model Rats

VernacularTitle:"针刺""足三里""穴干预胃肠功能紊乱-腹泻模型大鼠胃肠激素GAS、MTL水平的影响"
Author: Fang LI ; Fang GAO
Keywords: FGIDs; diarrhea; ST36; acupuncture; GAS; MTL; mechanism
From: Journal of Zhejiang Chinese Medical University 2017;41(4):271-273,277
CountryChina
Language:Chinese
Abstract: [Objective] To explore the mechanism of acupuncture at Zusanli point(ST36) in the treatment of functional gastrointestinal disorders(FGIDs). [Methods] A total of 40 Wistar rats were randomized into normal(n=10),model(n=10), Zusanli point(ST36),non-acupuncture point(n=10). FGIDs model was established by exerting the factors of cold-constraint stimulation and hunger disorder synthesis . And the content of rats serum and stomach tissue Gastrin (GAS) and Motilin(MTL) was observed by radioimmuno-assay. [ Results] Compared with the normal group, the content of rats serum and stomach tissue GAS and MTL of the model group was significantly reduced(P<0.01);Compared with the model group, the content of rats serum and stomach tissue GAS and MTL of ST36 group was significantly ascended(P<0.01);Compared with the non-acupuncture point group, the content of rats serum and stomach tissue GAS and MTL of ST36 group had statistically significant differences(P<0.01). [Conclusion] Acupuncture at ST36 had obvious improvement in FGIDs, its mechanism was closely related to GAS and MTL.