Application comparison of VDRL and TRUST in syphilis laboratory diagnosis
10.3969/j.issn.1673-4130.2017.07.015
- VernacularTitle:VDRL和TRUST在梅毒实验室诊断中的应用比较
- Author:
Weiying ZENG
;
Jinmei HUANG
;
Ping LYU
;
Jun ZHANG
;
Wujian KE
;
Tao HUANG
;
Sanmei TANG
;
Yahui LIU
- Keywords:
VDRL;
TRUST;
syphilis laboratory diagnosis
- From:
International Journal of Laboratory Medicine
2017;38(7):909-910,913
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the application of venereal disease research laboratory(VDRL) test and toluidine red unheated serum test(TRUST) in syphilis laboratory diagnosis.Methods Serum,plasma and cerebrospinal fluid (CSF) in syphilis patients and healthy controls were measured by VDRL and TRUST.Results The VDRL detection results in serum and CSF sepcimens were generally higher than the TRUST detection results by 1-2 titers,while in plasma specimen,the VDRL detection results were generally lower than the TRUST detection results by 1-2 titers than TRUST when using plasma specimen.In addition,the VDRL detection in normal control serum and plasma specimens all appeared different degrees of false positive,but in the detection of normal control CSF,the results of TRUST and VDRL were consistent.Conclusion TRUST is more suitable for serum and plasma specimens,and CSF is suitable for the CSF specimen,but not suitable for serum and plasma detection.