Study on the correlation between serum lipid level and anti-Müllerian hormone with embryo quality in vitro fertilization cycle

VernacularTitle:血脂水平与体外受精周期胚胎质量的相关性研究
Author: Songcheng GAO ; Yi LI ; Yan CHEN ; Liping WEN
Keywords: lipids; in vitro fertilization; embryo
From: International Journal of Laboratory Medicine 2017;38(8):1043-1044,1047
CountryChina
Language:Chinese
Abstract: Objective To study the relationship between serum lipid level with embryo quality in vitro fertilization cycle.Methods A total of 603 pairs of infertile couples who were treated with in vitro fertilization and embryo transfer technique (IVF-ET) in our hospital from October 2015 to June 2016 were collected.All subjects underwent long-term ovarian hyperstimulation,blood lipid and the embryo quality were measured and evaluated.Results Triglyceride (TG),total cholesterol (TC) and body mass index(BMI) were significantly negatively correlated with fertilization rate,2PN fertilization rate,cleavage rate and embryo rate (P<0.05).Density lipoprotein (LDL) and non-high density lipoprotein (NHDL) and lipoprotein (a) [Lp(a)] were negatively correlated with fertilization rate,2PN fertilization rate,high density lipoprotein.The cholesterol (HDL) were positively correlated with fertilization rate,2PN fertilization rate,cleavage rate and embryo rate(P>0.05).Conclusion There is a linear correlation between blood lipid level and AMI and embryo quality.Serum lipids and AMI can be used to evaluate the quality of embryo and provide suggestion for the quality control of IVF-ET.