Dynamic change of serum levels of perioperative infection factors and N-terminal brain natriuretic peptide in patients with lung cancer
10.3969/j.issn.1673-4130.2017.05.020
- VernacularTitle:肺癌围术期感染因子和N末端脑钠肽前体血清水平动态变化
- Author:
Yan WANG
;
Liying ZHONG
- Keywords:
lung cancer;
perioperative period;
infection factor;
procalcitonin;
dynamic monitoring
- From:
International Journal of Laboratory Medicine
2017;38(5):625-627,630
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the dynamic change of serum levels of perioperative procalcitonin (PCT ) ,C-reactive protein (CRP) ,interleukin 6(IL-6) and N-terminal brain natriuretic peptide(NT-proBNP) in the patients with lung cancer and to evaluate their value in postoperative monitoring .Methods Seventy-two patients with lung cancer were detected PCT ,CRP ,IL-6 and NT-proBNP levels before operation and on postoperative 1-5 d .The detection results were compared between the patients with cardiac injury and infection complications .Results Postoperative levels of serum PCT ,CRP ,IL-6 and NT-proBNP were increased in all the patients ;the peak value appearance of PCT ,CRP ,IL-6 and NT-proBNP in the patients with complications were earlier than that in the patients without complications ,moreover the peak value was significantly higher than that in the patients without complications (P<0 .05);the decrease speed of PCT ,CRP ,IL-6 and NT-proBNP in the patients with complications was slower than that in the patients without complications .Conclusion The combined detection of PCT ,CRP ,IL-6 and NT-proBNP may be become an effec-tive means to differentiate the postoperative complications .
