Clinicopathological features of small gastrointestinal stromal tumors
10.13315/j.cnki.cjcep.2016.12.004
- VernacularTitle:小胃肠间质瘤的临床病理学特征
- Author:
Lifang CUI
;
Jixin ZHANG
;
Hong CHANG
;
Hongyu ZHAO
;
Congling QU
;
Jianying ZHANG
;
Bing SHEN
- Keywords:
gastric neoplasms;
gastrointestinal stromal tumours;
small gastrointestinal stromal tumours;
microvascular density;
prognosis
- From:
Chinese Journal of Clinical and Experimental Pathology
2016;32(12):1334-1337,1342
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To assess the clinical and pathological features of small gastrointestinal stromal tumours (sGIST).Methods To reevaluated the clinical,histological and immunohistochemical parameters of 21 sGISTs.The standard immunohistochemical panel antibodies were studied on the tumor sections.All data were compared with clinical sGIST.Results There were a total of 7 females and 14 males of sGISTs.The median age was 63 years old.The tumors were predominantly located in the stomach showing a spindle cell morphology and the tumor sizes ranged from 0.5 cm to 1.5 cm.9 sGISTs combined with malignant tumors,which were gastric cancer have been incidentally detected during surgery.As the lesions were small in size,with infrequent bleeding,necrosis,mucosal invasion,ulceration and less mitotic index,sGISTs reoccurred less compared with clinical sGIST.p53,Ki-67 labeling index and microvascular density (MVD) in sGIST were significantly lower than clinical sGIST (P ＜ 0.05).Conclusion sGIST may occure with digestive tract cancer synchronously.p53,Ki-67 labeling index and MVD were lower than clinical GIST,which means better prognosis.
