Analysis on drug resistance of Mycoplasma pneumoniae isolated from children with community acquired pneumonia
10.3969/j.issn.1673-4130.2017.05.006
- VernacularTitle:儿童社区获得性肺炎分离的肺炎支原体耐药性分析
- Author:
Jinwen HUANG
;
Ruhai LI
;
Jiguang JIAO
- Keywords:
community acquired pneumonia;
Mycoplasma pneumoniae;
antibacterial drugs;
drug resistance
- From:
International Journal of Laboratory Medicine
2017;38(5):591-592,595
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the resistance to antibacterial drugs in Mycoplasma pneumoniae (Mp) isolated from the chil-dren with community acquired pneumonia (CAP) in Shiyan area .Methods A total of 426 throat swabs and serum samples were collected from children patients with suspected CAP in Shiyan area from Feb .2013 to Apr .2015 .The throat swabs were used to culture Mp .The serum Mp-IgM was detected by ELISA ,the positive samples were confirmed by plate culture method ,meanwhile , the drug sensitivity test was taken .Results Among 426 children cases ,69 cases were confirmed as Mp infection ;the drug suscepti-bility test results showed that the resistance rate of Mp was 76 .8(53/69) to erythromycin ,65 .2% (45/69) to azithromycin ,18 .8%(13/69) to levofloxacin ,4 .3% (3/69) to tetracycline ,4 .3% (3/69) to minocycline and 24 .6% (17/69) to gentamicin .Conclusion Mp is one of the key pathogens of CAP in Shiyan area ,which is severely resistant to macrolide .The treatment should choose sensi-tive drugs as the treatment drug ,but it is important to consider the toxicity and adverse reactions of these several kinds of drugs to children .The blind medication should be avoided .
