Effects of Danhongtongjing formula combined with levofloxacin on serum cytokines in patients with chronic prostatitis
10.3969/j.issn.1005-1678.2017.01.022
- VernacularTitle:丹红通精方联合左氧氟沙星对慢性前列腺炎患者血清细胞因子的影响及疗效
- Author:
Jiansheng WANG
;
Yujuan ZHANG
;
Yi ZHANG
;
Longfeng CHEN
- Keywords:
Danhongtongjing formula;
levofloxacin;
chronic prostatitis;
serum cytokines
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(1):84-86,90
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of Danhongtongjing formula combined with levofloxacin on serum cytokines in patients with chronic prostatitis. Methods 74 cases of patients with chronic prostatitis from May 2014 to April 2016 in our hospital were selected,and randomly divided into two groups,37 cases in each groups.The control group treated with levofloxacin,the observation group were treated with Danhongtongjing formula The observation group on the based of control group.The clinical symptoms,TCM syndrome and the changes of SIgA,VCAM-1 and serum VCAM-1 in prostatic fluid of two groups were compared. Results The total effective rate was 94.59% in the observation group and 78.38%in the control group,the difference was statistically significant (P<0.05).After treatment,the NIH-CPSI index of the two groups was significantly decreased,and the observation group was lower than the control group,the difference was statistically significant (P<0.05);the TCM syndrome score of both groups decreased,and the observation group was lower than the control group,the difference was statistically significant (P<0.05).The total effective rate of TCM Syndrome in observation group was 91.89%,which was significantly higher than that of the control group 72.97%,the difference was statistically significant (P<0.05).After treatment,the levels of SIgA,VCAM-1 and serum VCAM-1 in prostatic fluid were decreased,and the observation group was lower than the control group,the difference was statistically significant (P<0.05). Conclusion Danhongtongjing formula combined with levofloxacin in the treatment of chronic prostatitis patients with significant effect,can effectively regulate serum cytokines, control inflammation, improve the treatment efficiency.
