Effects of Fuzheng Xiaoai decoction joint tamoxifen on serum sex hormone and endometrial thickness with breast cancer
10.3969/j.issn.1005-1678.2017.03.036
- VernacularTitle:扶正消癌方联合他莫昔芬对乳腺癌术后患者血清性激素及子宫内膜厚度的影响研究
- Author:
Fuming LI
;
Danying XU
;
Yan YUAN
;
Yue LIU
;
Shuzhen FANG
- Keywords:
breastcancer;
tamoxifen;
Fuzheng Xiaoai decoction;
sex hormones;
endometrial thickness
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(3):122-124,127
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the effects of Fuzheng Xiaoai decoction joint tamoxifen on serum sex hormone and endometrial thickness with breast cancer.Methods 124 patients with breast cancer were divided into control group and research group by lot drawing method, all as 62 cases, treated with the same surgery, control group was treated with tamoxifen, research group was treated with Fuzheng Xiaoai decoction based on control group, the sex hormones, endometrial thickness, tumor markers, immune function and complications were compared between two groups.Results The prolactin (PRL), progesterone (P), estradiol (E2) of research group were all lower than control group, the difference were statistically significant (P<0.05).The endometrial thickness of research group [(8.61+1.07) mm]was lower than the control group [(9.74+1.21) mm](P<0.05).The tumor markers, immune function of research group were better than that of control group (P<0.05).The complications was no difference between two groups. Conclusion Fuzheng Xiaoai decoction joint tamoxifen can regulation the serum levels of sex hormone, relieve tamoxifen-induced endometrial thickening, can improve tumor markers and immune function .
